Catherine Zeta-Jones is set to join Blake Lively, Channing Tatum, and Jude Law in Steven Soderbergh’s upcoming Side Effects, sometimes known as The Side Effects, still known to IMDb as The Bitter Pill. Written by Soderbergh’s Contagion and The Informant! co-conspirator Scott Z. Burns, the film will feature Zeta-Jones playing doctor to a depressed, massively prescription-drugged Lively. It’ll be Zeta-Jones’s second third go-round with Soderbergh, following 2000’s Traffic and 2004’s Ocean’s Twelve. Production is slated to begin in New York in April.