Chris O’Dowd may reunite with his Bridesmaids co-star Melissa McCarthy in St. Vincent De Van Nuys, a new comedy-drama that has Bill Murray in the lead role. Deadline reports that O’Dowd is in “early talks†to join the cast as a nice Catholic priest who is concerned about Murray’s cranky misanthrope character mentoring a 12-year-old neighbor boy whose hardworking single mom (McCarthy) unwisely leaves him in Murray’s hands. St. Vincent is the feature film debut of writer/director Ted Melfi, who has a fun Bill Murray story just like everybody who works with Bill Murray does. Chris O’Dowd will probably have one soon too.