In his first role since wrapping Lost almost a year ago, Matthew Fox has committed to star as the villain in I, Alex Cross, the big-screen adaptation of James Patterson’s book series, which will star Tyler Perry in the title role (Morgan Freeman was Cross in Kiss the Girls and Along Came a Spider). Fox will play a mob hitman nicknamed “The Butcher†who kills Cross’s wife (this is why you can’t get married, Tyler), a story line pulled from a different Alex Cross book, but who’s counting? The two then engage in a battle of wits to defeat each other; no word yet on whether this will involve outlandish, cross-dressing disguises. [Deadline]