Mandy Moore is set to take the lead role in a single-camera comedy for ABC called Us and Them. The singer-actress, who has guest-starred on Grey’s Anatomy, Scrubs, Entourage, and How I Met Your Mother, will play a character negotiating the “inherent conflict†between her immediate family and her new husband. So far, there’s no word on Moore’s male co-star, though Wedding Crashers writer Ben Fisher is responsible for the script. The project will also reunite her with producer Jon Leshay, who had a hand in her most memorable (in a good and bad way, respectively) film jobs, Saved and A Walk to Remember. [Deadline]